Curriculum académique
Academic curriculum
Curriculum académique
Academic curriculum
* Curriculum vitae complet disponible sur demande // Full curriculum vitae available on request *
Diplômes :
M.D. - Université Laval (2015-2020)
Ph.D Medical microbiology - University of Manitoba (2010-2015)
Thèse: Proteomic host responses and growth properties of highly pathogenic H5N1 and novel H7N9 avian influenza strains.
M.Sc. Microbiologie-Immunologie - Université Laval (2008-2010)
Sujet de mémoire : Caractérisation in vitro des capacités réplicatives de souches saisonnières d'influenza résistantes à l'oseltamivir // In vitro characterisation of replication capacities of seasonal oseltamivir-resistant influenza strains
B.Sc. Microbiologie - Université de Sherbrooke (2005-2008)
Deux stages // Two internships.
Été / Summer 2007 : Kenya Medical Research Institute (Nairobi, Kenya) - Arbovirologie
Été / Summer 2006 : Gorgas Institute (Panama, Panama) - Hantavirus
Financement / Scholarships
Bourse Doctorale // Doctoral award - Fond de la Recherche en Santé du Québec (FRSQ, 2011 - 2014)
PhD award (declined) // Bourse de PhD (déclinée) - Manitoba Health Research Council (MHRC, 2011 - 2013)
Publications :
Ting Lin W, Simon P et al. The Natural Product Triptolide Inhibits Influenza Virus Replication. In progress June 2018
McLeish N, Simon P et al. Small molecule modulator of the Wnt/β-Catenin signaling pathway is a potent inhibitor of seasonal and avian Influenza H5N1 and H7N9 viruses. In progress June 2018
Simon P et al. Avian influenza viruses that cause highly virulent infections in humans exhibit distinct replicative properties in contrast to human H1N1 viruses. Scientific Reports. 2016 Apr 15;6:24154
Simon P et al. Highly Pathogenic H5N1 and Novel H7N9 Influenza A Viruses Induce More Profound Proteomic Host Responses than Seasonal and Pandemic H1N1 Strains. J Proteome Res. 2015 Nov 6;14(11):4511-23
Clark CG, Chong PM, McCorrister SJ, Simon P et al. The CJIE1 prophage of Campylobacter jejuni affects protein expression in growth media with and without bile salts. BMC Microbiol. 2014 Mar 19;14:70
Huzarewich R, Simon P et Booth S. 2013. Prion Biomarkers in Proteomics in Food Microbiology and Food Safety Vol 2 pp.547-61. Springer Editiors
Holder BP* and Simon P* et al. Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model. PLoS ONE 2011 Mar 24;6(3):e14767.
* Premiers co-auteurs / First co-authors
Holder BP, Liao L, Simon P, Boivin G and Beauchemin CA. Design consideration in building in silico equivalents of common experimental influenza virus assays and the benefit of such an approach. Autoimmunity. 2011 Jun;44(4):282-93.
Simon P et al.The I222V neuraminidase mutation has a compensatory role in the replication of an oseltamivir-resistant A/H3N2 E119V mutant. J Clin Microb. 2011 Feb; 49(2):715-7.
Abed Y, Simon P, Boivin G. Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation. Antimicrob Agents Chemother. 2010 Jul;54(7):2819-22.
Baz M, Abed Y, Simon P, Hamelin M-E, Boivin G. Impact of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent influenza A/H1N1 viruses. J Infect Dis. 2010 Mar;201(5):740-5.
Conférences nationales / internationales :
International Congress of Virology 2014 (ICV - Montréal, QC) : Oral presentation
Prairie Infectious Immunology Network 2014 (PIIN - Hecla, MB) : Poster
Prairie Infectious Immunology Network 2012 (PIIN - Moose Jaw, SK) : Poster
American Society for Virology 2012 (ASV - Madison, WI) : Oral presentation
American Society for Mass Spectrometry 2012 (ASMS - Vancouver, BC): Poster
Interscience Conference on Antimicrobial Agents and Chemotherapy 2009 ( ICAAC - San Francisco, CA) : Poster
Langues
Français, English, Español
Extra-Curriculaire
Président du Department of medical microbiology graduate student council (University of Manitoba, 2013-2014)
Président du CÉCRI - (Université Laval, 2009-2010)
Officier Médical (Medical Officer) - Service de Santé Royal Canadien (2017- )
Technicien Médical (Medic) NQ4 - Service de Santé Royal Canadien (2006-2017)
Capitaine et propriétaire du S/V Le Champenois, un Halman Horizon 27
Captain and owner of S/V Le Champenois, a Halman Horizon 27