* Curriculum vitae complet disponible sur demande // Full curriculum vitae available on request *

Diplômes :

M.D. - Université Laval (2015-2020)

Ph.D Medical microbiology - University of Manitoba (2010-2015)

Thèse: Proteomic host responses and growth properties of highly pathogenic H5N1 and novel H7N9 avian influenza strains.

M.Sc. Microbiologie-Immunologie - Université Laval (2008-2010)

Sujet de mémoire : Caractérisation in vitro des capacités réplicatives de souches saisonnières d'influenza résistantes à l'oseltamivir // In vitro characterisation of replication capacities of seasonal oseltamivir-resistant influenza strains

B.Sc. Microbiologie - Université de Sherbrooke (2005-2008)

Deux stages // Two internships.

Été / Summer 2007 : Kenya Medical Research Institute (Nairobi, Kenya) - Arbovirologie   

Été / Summer 2006 : Gorgas Institute (Panama, Panama) - Hantavirus

Financement / Scholarships

Bourse Doctorale // Doctoral award  - Fond de la Recherche en Santé du Québec (FRSQ, 2011 - 2014)

PhD award (declined) // Bourse de PhD (déclinée) - Manitoba Health Research Council (MHRC, 2011 - 2013)

Publications :

Ting Lin W, Simon P et al. The Natural Product Triptolide Inhibits Influenza Virus Replication. In progress June 2018

McLeish N, Simon P et al. Small molecule modulator of the Wnt/β-Catenin signaling pathway is a potent inhibitor of seasonal and avian Influenza H5N1 and H7N9 viruses. In progress June 2018

Simon P et al. Avian influenza viruses that cause highly virulent infections in humans exhibit distinct replicative properties in contrast to human H1N1 viruses. Scientific Reports. 2016 Apr 15;6:24154

Simon P et al. Highly Pathogenic H5N1 and Novel H7N9 Influenza A Viruses Induce More Profound Proteomic Host Responses than Seasonal and Pandemic H1N1 Strains. J Proteome Res. 2015 Nov 6;14(11):4511-23

Clark CG, Chong PM, McCorrister SJ, Simon P et al. The CJIE1 prophage of Campylobacter jejuni affects protein expression in growth media with and without bile salts. BMC Microbiol. 2014 Mar 19;14:70

Huzarewich R, Simon P et Booth S. 2013. Prion Biomarkers in Proteomics in Food Microbiology and Food Safety Vol 2 pp.547-61. Springer Editiors

Holder BP* and Simon P* et al. Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model. PLoS ONE 2011 Mar 24;6(3):e14767.                

* Premiers co-auteurs / First co-authors

Holder BP, Liao L, Simon P, Boivin G and Beauchemin CA. Design consideration in building in silico equivalents of common experimental influenza virus assays and the benefit of such an approach. Autoimmunity. 2011 Jun;44(4):282-93.

Simon P et al.The I222V neuraminidase mutation has a compensatory role in the replication of an oseltamivir-resistant A/H3N2 E119V mutant. J Clin Microb. 2011 Feb; 49(2):715-7.

Abed Y, Simon P, Boivin G. Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation. Antimicrob Agents Chemother. 2010 Jul;54(7):2819-22.

Baz M, Abed Y, Simon P, Hamelin M-E, Boivin G. Impact of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent influenza A/H1N1 viruses. J Infect Dis. 2010 Mar;201(5):740-5.

Conférences nationales / internationales :

International Congress of Virology 2014 (ICV - Montréal, QC) : Oral presentation

Prairie Infectious Immunology Network  2014 (PIIN - Hecla, MB) : Poster

Prairie Infectious Immunology Network  2012 (PIIN - Moose Jaw, SK) : Poster

American Society for Virology 2012 (ASV - Madison, WI) : Oral presentation

American Society for Mass Spectrometry 2012 (ASMS - Vancouver, BC): Poster

Interscience Conference on Antimicrobial Agents and Chemotherapy 2009 ( ICAAC - San Francisco, CA) : Poster

Langues

Français, English, Español

Extra-Curriculaire

Président du Department of medical microbiology graduate student council (University of Manitoba, 2013-2014)

Président du CÉCRI - (Université Laval, 2009-2010)

Officier Médical (Medical Officer) - Service de Santé Royal Canadien (2017- )

Technicien Médical (Medic) NQ4 - Service de Santé Royal Canadien (2006-2017)

Capitaine et propriétaire du S/V Le Champenois, un Halman Horizon 27
Captain and owner of S/V Le Champenois, a Halman Horizon 27